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RAISE-Vision: An Automated Contact Angle Measurement Platform for Contact Lens Wettability Characterization

RAISE-Vision is an automated platform for contact angle (CA) measurement on curved hydrogel surfaces, intended for in vitro wettability analysis of contact lenses. Its 3D-printed lens mounts, camera holders, and drying apparatus enable an automated, repeated sessile-drop workflow within a liquid handling system. A custom open-source image processing script combines elliptical fitting and the tangent method to handle droplet deformation on curved surfaces. In 10 consecutive measurements of a senofilcon A lens in air, the contact angle rose from 62.6±5.5° to 83.4±2.1°, with no significant difference from the manual protocol results (p=0.470).

Part of the event: RAISE-Vision Automatically Measures Contact Angle of Contact Lenses

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